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Nucleic Acid Therapeutics

formerly Oligonucleotides

Co-Editors-in-Chief: Bruce A. Sullenger, PhD
and Annemieke Aartsma-Rus, PhD

Executive Editor
: Graham C. Parker, PhD

ISSN: 2159-3337 • Online ISSN: 2159-3345 • Published Bimonthly

Current Volume: 26

Latest Impact Factor* is 2.813

*2015 Journal Citation Reports® published by Thomson Reuters, 2016

Liebert Open Access Publish open access in this Journal.

Featured Press Releases and Editorial Content

  • More Potent, Inexpensive Gene Silencing Agents Described in Nucleic Acid Therapeutics...Read More
  • Are Some People More Likely to Develop Adverse Reactions to Nanoparticle-Based Medicines?...Read More
  • Can a "Sense" DNA Drug Reverse the Actions of an Antisense Drug to Treat Blood Clots and Prevent Bleeding?...Read More 
  • Novel Therapeutic Strategy for Single Gene Disorders Delivers RNA That Encodes the Missing Protein...Read More
  • New Gene Therapy Method Provides Specific, Safe Control of Therapeutic Transgenes...Read More
  • New Aptamer-Based Approach Delivers microRNA Therapeutic That Targets Cancer and Cardiovascular Disease...Read More
  • New, Natural DNA-Based Drugs Are Safe, Potent Activators of Immune System...Read More
  • Nanoparticles that Deliver Oligonucleotide Drugs into Cells...Read More
  • New Guidelines for Reproductive & Developmental Toxicity Testing of Oligonucleotide Drugs...Read More
  • Novel RNAi-Based Therapy for Anemia Stimulates Liver to Produce EPO...Read More
  • Industry Group Releases Safety Testing Recommendations for Oligonucleotide-Based Therapeutics...Read More
  • RNA Aptamers Targeted to Plasminogen Activator Inhibitor Can Block Its Anti-Clot-Busting Activity...Read More
  • Special Issue on Exon Skipping
  • Exon Skipping Prevents Formation of Toxic Protein Fragments in Huntington's Disease...Read More
  • A Natural Sugar Delivers DNA Aptamer Drug Inside Tumor Cells...Read More


Nucleic Acid Therapeutics is the leading journal in its field focusing on cutting-edge basic research, therapeutic applications, and drug development using nucleic acids or related compounds to alter gene expression. The Journal examines many new approaches for using nucleic acids as therapeutic agents or in modifying nucleic acids for therapeutic purposes including: oligonucleotides, gene modification, aptamers, RNA nanoparticles, and ribozymes.  

Nucleic Acid Therapeutics coverage includes:

  • RNAi: siRNAs, shRNAs, and miRNAs
  • Antisense applications; nucleoside and nucleotide analogs and modifications
  • Peptide nucleic acids
  • DNA-modified gene therapy
  • Nucleic acid-based nanoparticles
  • Ethical, legal, and regulatory issues

Nucleic Acid Therapeutics is under the editorial leadership of Editor-in-Chief Bruce A. Sullenger, PhD, Duke Translational Research Institute, Duke University Medical Center; Executive Editor Graham C. Parker, PhD; and other leading investigators. View the entire editorial board.  

Audience: Molecular biologists, biochemists, DNA and cell biologists, and biopharmaceutical researchers, among others.  

Nucleic Acid Therapeutics is a rapid-publication Journal, with peer review averaging 25 days from submission to first decision, and online publication of the article within four weeks of acceptance.

Society Affiliation

OTSThe Official Journal of Oligonucleotide Therapeutics Society (OTS).

Indexed/Abstracted in:

MEDLINE; PubMed; PubMed Central; Current Contents®/Life Sciences; Science Citation Index Expanded; Social Sciences Citation Index®; Biotechnology Citation Index®; Biological Abstracts; BIOSIS Previews; Journal Citation Reports/Science Edition; Derwent Drug File; EMBASE/Excerpta Medica; EMBiology; Scopus; ProQuest databases; SIIC Data Bases

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The views, opinions, findings, conclusions and recommendations set forth in any Journal article are solely those of the authors of those articles and do not necessarily reflect the views, policy or position of the Journal, its Publisher, its editorial staff or any affiliated Societies and should not be attributed to any of them.

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