Call for Papers

Microgravity and Stem Cell Research

Guest Editor

Elizabeth Blaber, PhD
Visiting Research Scientist, USRA
Space Biosciences Division, NASA Ames Research Center

Exposure to spaceflight conditions, including microgravity and radiation, is known to have significant effects on mammalian physiology. Spaceflight (Space Shuttle and ISS) and simulated microgravity experiments have resulted in the identification of changes to almost every physiological system ranging from individual molecules and cells, to broad tissue and systemic changes. The fundamental cause of many of these alterations have yet to be fully elucidated and the physiological consequences of these changes are currently unknown.

Alterations to fundamental stem cell properties may have significant implications for the establishment of long-term colonies on extra-terrestrial bodies, including Mars and asteroids. Therefore, elucidation of the molecular and cellular mechanisms causing changes to stem cell function will have broad implications for understanding fundamental mechanisms of stem cell repair and regeneration and Earth-based degenerative conditions, and will aid in our understanding of the effects of long-duration spaceflight on mammalian health and regenerative function.

In this issue, we invite papers investigating the effects of microgravity on specific stem cell function, including changes to both embryonic stem cells and tissue specific stem cells. Papers may address the following topic areas in relation to microgravity effects:

  • Tissue regeneration
  • Embryonic stem cells and development
  • Germ cells and reproductive health
  • Tissue specific stem cell function, including but not restricted to mesenchymal, hematopoietic, neural and intestinal stem cells
  • Alterations to stem cell morphology and implications for function
  • Changes in extracellular matrix components and adhesion mechanisms affecting stem cell function
  • Influence on systemic factors, e.g. oxidative stress, hormonal changes, inflammation 

Visit the Stem Cells and Development website for manuscript submission guidelines. We look forward to receiving your manuscripts and to your active participation in the Journal!

Benefits of publishing in the journal:

  • Rapid, rigorous peer-review
  • Open Access options available
  • Maximum exposure: accessible in 170 countries worldwide
  • Indexed in key indexing services
  • New end-to-end Author Benefits Program

Learn More about this journal

Deadline for Manuscript Submission:
December 1, 2017


For questions, please contact:

Guest Editor Elizabeth Blaber, PhD or
Editor-in-Chief Graham Parker, PhD