Tissue Engineering Researcher Spotlight

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Dr. Robby Bowles, Ph.D.

Dr. Robby Bowles, Ph.D.

Assistant Professor, Department of Bioengineering
University of Utah

Dr. Bowles's lab is focused on engineering cell function to better control tissue development in engineered tissues. He utilizes recent advances in CRISPR epigenome regulation of gene expression to precisely control cell activity in engineered tissues and is specifically interested in applying these techniques for use in tissue engineering, gene therapy, and immunoengineering to modulate tissue development and intervertebral disc degeneration for the treatment of back pain. Focused on back pain, a leading cause of disability, his lab is focused on modulating the interactions between the biomechanics of the intervertebral disc, the inflammatory environment of the intervertebral disc and the peripheral nervous system to both develop a better understanding of back pain and to develop novel therapeutics.

For more, read about Dr. Bowles's recent work in Tissue Engineering Part A:

Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD. CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. Tissue Engineering Part A. 2017 Feb 28.