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Advances in Tissue Engineering, Volume 1: Angiogenesis

Editors: Peter C. Johnson, MD and Antonios G. Mikos, PhD

2010 • ISBN13 978-1-934854-16-7 • ISBN e-book 978-1-934854-17-4
Hardcover • 310 pages, 175 illus; 68 color • Trim size: 8-1/2 x 11

Overview

Angiogenic control has proven to be one of the most difficult aspects of tissue engineering to master. This presents broad-based anatomic and physiologic challenges to the tissue engineer. Key controllers of angiogenesis have been formed to be mechanical forces, small molecules (drugs and growth factors), co-culture with non-vascular cells, biomaterials, and stem cells. This volume addresses vascular assembly techniques and the transplantation of microvascular networks.

Advances in Tissue Engineering, Volume 1: Angiogenesis presents leading-edge research and insight on:

  • The mechanisms of angiogenesis, as studied in developmental biology models
  • The application of systems biology to help us understand how choke points might be controlled by drugs or other approaches
  • The physiological functioning of engineered capillaries, venules, and arterioles
  • Creation of networks that have large enough arterial and venous components to enable direct anastomosis to host vessels
  • Vascular assembly techniques and transplantation of microvascular networks
 

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