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Human Gene Therapy

Editor-in-Chief: Terence R. Flotte, MD
Deputy Editors, Europe: Nathalie Cartier, MD and Thierry VandenDriessche, PhD
Deputy Editors, U.S.: Barry J. Byrne, MD, PhD and Mark A. Kay, MD, PhD
Human Gene Therapy Editor: Guangping Gao, PhD
Methods Editor: Hildegard Büning, PhD
Clinical Development Editor: James M. Wilson, MD, PhD

ISSN: 1043-0342 • Online ISSN: 1557-7422 • Published 22 issues annually

Current Volume: 28

Latest Impact Factor* is 4.187

*2016 Journal Citation Reports® (Clarivate Analytics, 2017)

Liebert Open Access Publish open access in this Journal.
LiebertOpenAccess.com

Human Gene Therapy Methods Latest Impact Factor* 1.831 
Human Gene Therapy Clinical Development Latest Impact Factor* 2.490 

Featured Press Releases and Editorial Content

  • Researchers Describe Novel Reporter Proteins for Tracking Long Term Expression of Therapeutic Genes...Read More
  • Intranasal Gene Delivery: Noninvasive Approach Shows Efficacy for Preventing Neurologic Effects of Inherited Metabolic Disease...Read More
  • Prednisone May Improve Effectiveness of AAV-Based Gene Therapy by Reducing Immune Response...Read More
  • Safety of Gene Transfer to Treat Heart Failure Supports Further Clinical Development...Read More
  • What Causes Gene Transfer to Trigger T Cell Activation and Exhaustion?...Read More
  • New Studies Refocus Attention on the Genotoxicity of Adeno-associated Viral Vectors in Gene Therapy...Read More
  • Debate Continues Over Human Immune System's Role in Blocking Therapeutic Genes Delivered Using AAV Vectors...Read More
  • Researchers Improve Vectors for Delivering Human Factor VIII Gene Therapy to Treat Hemophilia A...Read More
  • Will AAV Vectors Have a Role in Future Novel Gene Therapy Approaches?...Read More
  • Feng Zhang Discusses CRISPR and Future of Gene Editing
    in Interview in Human Gene Therapy...Read More
  • AAV Gene Delivery Vectors and Cancer -- The Debate Continues...Read More
  • New Approach to Improve Therapeutic Gene Delivery to Arthritic Joints...Read More
  • What Changes Are Needed to Sustain a Vibrant Workforce of PhD Biomedical Scientists?...Read More
  • New System for Therapeutic Gene Delivery Increases Transgene Expression Up To 100-fold...Read More
  • Gene Delivery to the Lung Can Treat Broad Range of Diseases Within and Beyond the Lung...Read More
  • Katherine High Discusses Progress and Challenges in Gene Therapy for Hemophilia and Inherited Retinopathies...Read More
  • Gene Therapy for Liver Disease Advancing With the Help of Adeno-associated Viral Vectors...Read More
  • Gene Therapy to Prevent Vision Loss: Studies in Primates Needed to Optimize Human Trials...Read More
  • What Changes Are Needed to Sustain a Vibrant Workforce of PhD Biomedical Scientists?... Read More
  • Promising Safety and Efficacy Results With Novel Lentiviral-Based Gene Therapy for SCID...Read More
  • Novel Mapping Technique Targets Gene Therapy to Hibernating Heart Muscle...Read More
  • Pancreatitis Reduced by Nearly 50% After Gene Therapy to Treat Lipoprotein Lipase Deficiency...Read More
  • Positive Clinical Trial Results from Dr. Peter Campochiaro on Gene Transfer to Treat Macular Degeneration...Read More
  • New Safety Data Support Human Testing of Hematopoietic Stem Cell Gene Therapy for Mucopolysaccharidosis I...Read More
  • Long-Term Study Shows Less Frequent and Severe Pancreatitis Following Gene Therapy for LPLD...Read More
  • Impact of BREXIT on Gene and Cell Therapy in the UK...Read More
  • Study Demonstrates Feasibility of Therapeutic Gene Delivery for Inherited Retinal Degeneration in Children...Read More
  • Gene Editing of Blood Stem Cells Can Correct Disease-Causing Mutations...Read More
  • Advances in Stem Cell Therapy to Treat Neurogenetic Diseases...Read More
  • How Does Immune Response Differ for Natural Adeno-Associated Virus Infection Compared to AAV Vector for Gene Transfer?...Read More
  • Promising Results with New Gene Therapy Approach for Treating Inherited Neurodegenerative Diseases...Read More
  • New Study Shows Long-term Safety of Gene Therapy in Parkinson's Disease...Read More
  • Clinical Advances in Gene Therapy for Central Nervous System Disorders...Read More
  • New Gene Therapy Strategies Emerging to Combat Vision Loss...Read More
  • Does AAV-Based Gene Delivery Cause Liver Cancer? The Debate Heats Up...Read More
  • Junction Opening Protein Boosts Cancer-Killing Effect of Oncolytic Virus...Read More
  • What Can We Learn From Zebrafish About Human Blood Disorders?...Read More
  • Progress and Promise of Gene Transfer and Gene Editing To Cure Beta-Thalassemias...Read More
  • Newly Identified Host Defense Mechanism Protects Cells From Viral Infection...Read More
  • Promising Results Reported in Study of AAV-based Gene Delivery to Treat Methylmalonic Acidemia...Read More
  • Major Advances and Ongoing Challenges for Gene Therapy in SCID-X1...Read More
  • Non-integrating Viral Vector Successfully Delivers Chemotherapy-Sensitizing Gene to Pancreatic Cancer Cells...Read More
  • Update on Advances in Gene Therapy From National Center for Advancing Translational Sciences...Read More
  • Can Gene Therapy Provide a Breakthrough in Alzheimer's Disease?...Read More
  • Proposed Link Between Liver Cancer and Adeno-Associated Virus Challenged...Read More
  • Discovering the Secret to Success and Innovation in Commercializing Biotechnology...Read More
  • Is The First Commercial Gene Therapy Product Within Sight?...Read More
  • Terry Flotte, MD Appointed New Editor-in-Chief of Human Gene Therapy...Read More

Overview

Human Gene Therapy is the premier, multidisciplinary journal covering all aspects of gene therapy. The Journal publishes in-depth coverage of DNA, RNA, and cell therapies by delivering the latest breakthroughs in research and technologies. Human Gene Therapy provides a central forum for scientific and clinical information, including ethical, legal, regulatory, social, and commercial issues, which enables the advancement and progress of therapeutic procedures leading to improved patient outcomes, and ultimately, to curing diseases.

The Journal is divided into three parts. Human Gene Therapy, the flagship, is published 12 times per year. HGT Methods, a bimonthly journal, focuses on the applications of gene therapy to product testing and development. HGT Clinical Development, a quarterly journal, serves as a venue for publishing data relevant to the regulatory review and commercial development of cell and gene therapy products.

Complete HGT Program coverage includes:

  • Improvements in vector developments
  • Delivery systems
  • Cell therapy
  • Small nucleic acid therapeutics, including RNAi
  • Clinical trials and animal models
  • Clinical protocols
  • Pre-clinical animal and in vitro studies to assess the safety of gene and cell therapy products used to support clinical applications
  • Clinical trials including those in which the results are confirmatory or negative
  • Topical issues related to the commercial development of gene and cell therapy products

Human Gene Therapy was voted one of the most influential journals in Biology and Medicine over the last 100 years by the Biomedical & Life Sciences Division of the Special Libraries Association.

Human Gene Therapy, HGT Methods, and HGT Clinical Development are under the editorial leadership of Editor-in-Chief Terence R. Flotte, MD, University of Massachusetts Medical School; Deput Editors Europe Nathalie Cartier, MD, INSERM, and Thierry VandenDriessche, PhD, Free University of Brussels (VUB); Deputy Editors U.S. Barry J. Byrne, MD, PhD, Powell Gene Therapy Center, University of Florida, College of Medicine and Mark A. Kay, MD, PhD, Stanford University School of Medicine; Human Gene Therapy Editor Guangping Gao, PhD, University of Massachusetts Medical School; Methods Editor Hildegard Büning, PhD, University of Cologne; Clinical Development Editor James M. Wilson, MD, PhD, University of Pennsylvania School of Medicine, Gene Therapy Program; and other leading investigators. View the entire editorial board.

Audience: Geneticists, medical geneticists, molecular biologists, virologists, experimental researchers, and experimental medicine specialists, among others.

Human Gene Therapy and HGT Methods provide “Instant Online” publication 72 hours after acceptance

This subscription includes:


Read Online

Editor-in-Chief: Terence R. Flotte, MD
ISSN: 1043-0342 • Monthly • Online ISSN: 1557-7422
Editorial Board   •   Author Information   •   Subscribe

Human Gene Therapy is the definitive peer-reviewed rapid-publication journal covering all aspects of human gene therapy.  The Journal publishes scientific papers on original investigations into the transfer and expression of genes in mammals, including humans with in-depth coverage of DNA, RNA, and cell therapies. Improvements in vector development, delivery systems, and animal models, particularly in the areas of cancer, heart disease, viral disease, genetic disease, and neurological disease, are covered. 



Read Online

Editor-in-Chief: Terence R. Flotte, MD
ISSN: 1946-6536  • Bimonthly  •  Online ISSN: 1946-6544
Editorial Board  •   Author Information  •  Subscribe

Human Gene Therapy Methods (HGT Methods) publishes technological advances in cell and gene therapy that promote the development of gene therapy products into successful therapeutics. The Journal breaks new ground as the first to exclusively focus on the applications of gene therapy to product testing and development.



Read Online

Editor-in-Chief: Terence R. Flotte, MD
ISSN: 1043-0342  • Quarterly  •  Online ISSN: 1557-7422
Editorial Board  •   Author Information  •  Subscribe

Human Gene Therapy Clinical Development publishes data relevant to the regulatory review and commercial development of cell and gene therapy products. Pre-clinical papers focus on pharmacology/toxicity/bio-distribution experiments used in the review of proposed clinical trials and will contain sufficient information to allow referencing between products within the same technology platform when appropriate.


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The Official Journal of nine international societies:

DG-GT e.V.

 

Indexed/Abstracted in:

MEDLINE; PubMed; PubMed Central; Current Contents®/Life Sciences; Science Citation Index Expanded; Science Citation Index®; Biotechnology Citation Index®; Biological Abstracts; BIOSIS Previews; Journal Citation Reports/Science Edition; Derwent Drug File; EMBASE/Excerpta Medica; EMBiology; Scopus; Chemical Abstracts; ProQuest databases
 

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The views, opinions, findings, conclusions and recommendations set forth in any Journal article are solely those of the authors of those articles and do not necessarily reflect the views, policy or position of the Journal, its Publisher, its editorial staff or any affiliated Societies and should not be attributed to any of them.

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