Research Article
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Published Online: 17 June 2016

Searching for Evidence to Support the Use of Ginger in the Prevention of Chemotherapy-Induced Nausea and Vomiting

Publication: The Journal of Alternative and Complementary Medicine
Volume 22, Issue Number 6

Abstract

Patients with cancer frequently use dietary supplementation and herbal therapies to control symptoms of disease and adverse effects of cancer therapy. Despite the widespread use of dietary supplementation and herbal therapies in oncology, robust scientific evidence in this area is lacking. Not only do these products need to be tested in large and well-designed observational or randomized studies, but their manufacturing process must be improved to achieve higher levels of standardization in product quality. Ginger is frequently used to counteract chemotherapy-induced nausea and vomiting (CINV), and some suggestions that it might be effective against CINV come from randomized and/or crossover clinical trials. However, several limitations in the methods of these studies limit their power and generalizability. The authors are conducting a randomized, double-blind study with a large sample size and homogeneous inclusion criteria in order to evaluate the efficacy of a well-standardized ginger extract in reducing nausea in patients with cancer. The widespread use of standardized herbal therapies and natural components among patients requires that scientific and rigorous research strategies are applied in this field to guide the physicians and the patients in safer use.

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Information & Authors

Information

Published In

cover image The Journal of Alternative and Complementary Medicine
The Journal of Alternative and Complementary Medicine
Volume 22Issue Number 6June 2016
Pages: 486 - 488
PubMed: 27115042

History

Published online: 17 June 2016
Published in print: June 2016
Published ahead of print: 26 April 2016

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Authors

Affiliations

Paolo Bossi
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
Diego Cortinovis
Ospedale San Gerardo, Monza, Italy.
Maria Cossu Rocca
Istituto Europeo di Oncologia, Milano, Italy.
Fausto Roila
Ospedale Santa Maria, Terni, Italy.
Patrizia Seminara
Università Sapienza, Roma, Italy.
Alessandra Fabi
Istituto Nazionale Tumori Regina Elena, Roma, Italy.
Stefania Canova
Ospedale San Gerardo, Monza, Italy.
Elena Verri
Istituto Europeo di Oncologia, Milano, Italy.
Sonia Fatigoni
Ospedale Santa Maria, Terni, Italy.
Alessandro Iannace
Università Sapienza, Roma, Italy.
Fabio Macchi
Helsinn Integrative Care, Lugano, Switzerland.
Carla Ripamonti
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

Notes

Address correspondence to:Paolo Bossi, MDFondazione IRCCS Istituto Nazionale dei TumoriVia Venezian 1Milano 20133Italy
E-mail: [email protected]

Author Disclosure Statement

Fabio Macchi is the head of Scientific and Clinical Portfolio Development at Helsinn Integrative Care, a division of Helsinn Healthcare SA, Lugano, Switzerland. For all other authors, no competing financial interests exist.

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