Effect of a Smartphone Application Incorporating Personalized Health-Related Imagery on Adherence to Antiretroviral Therapy: A Randomized Clinical Trial
Publication: AIDS Patient Care and STDs
Volume 28, Issue Number 11
Abstract
Poor adherence to combination antiretroviral therapy (ART) is a major global challenge. In this study we examined the efficacy of a smartphone application incorporating personalized health-related visual imagery that provided real-time information about the level of medication and the patient's level of immunoprotection, in order to improve adherence to ART. We randomized 28 people on ART to either a standard or augmented version of the smartphone application. The augmented version contained components that illustrated participants' current estimated plasma concentrations of antiretroviral drugs and the immune protection provided by ART. Adherence to ART was assessed at baseline and at 3 months using self-reported adherence, pharmacy dispensing records, and HIV viral load. Information was also collected on illness and medication beliefs and use of the application. Participants who received the augmented application showed a significantly higher level of self-reported adherence to ART at 3 months (p=0.03) and decreased viral load (p=0.023) as compared to individuals using the standard version. Greater usage of the extra components of the augmented application was associated with greater perceived understanding of HIV infection and increased perceived necessity for ART. Smartphone applications that incorporate personalized health-related visual imagery may have potential to improve adherence to ART.
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Information & Authors
Information
Published In
AIDS Patient Care and STDs
Volume 28 • Issue Number 11 • November 2014
Pages: 579 - 586
PubMed: 25290556
Copyright
Copyright 2014, Mary Ann Liebert, Inc.
History
Published online: 3 November 2014
Published in print: November 2014
Published ahead of print: 7 October 2014
Authors
Author Disclosure Statement
No competing financial interests exist.
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