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Published Online: 29 April 2009

Minimally Invasive Palliative Tumor Therapy Guided by Imaging Techniques: The UCLA Experience

Publication: Journal of Clinical Laser Medicine & Surgery
Volume 12, Issue Number 2


Imaging-guided palliative therapy of recurrent and/or inaccessible head and neck tumors may soon become clinically practical since sensitive and noninvasive monitoring techniques of energy deposition in tissues are now available. Interstitial tumor therapy (ITT) is a technique whereby a source of energy (laser, radiofrequency, ultrasonic, cryoenergy, etc.) is directly applied into tumors at various depths. Recent1–12 studies have demonstrated the efficiency of ultrasound (UTZ) and magnetic resonance imaging (MRI) for real and/or "near" real time tumor and vessel identification as well as monitoring and quantifying energy-induced tissue damage. We now report our initial clinical experience with patients in which UTZ and/or MRI-guided ITT techniques were successfully applied for the treatment of recurrent, nonresectable, local, and/or metastatic head and neck carcinomas. Patients were treated on an outpatient basis either in the operating room or in an upgraded specially equipped SIGNA 1.5T MR suite. Most patients tolerated these procedures well and were successfully palliated for periods ranging from 3 months to 5 years posttreatment. The upgrades introduced in a standard MRI suite, the clinical experience, and future perspectives will be reviewed.

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cover image Journal of Clinical Laser Medicine & Surgery
Journal of Clinical Laser Medicine & Surgery
Volume 12Issue Number 2April 1994
Pages: 65 - 73
PubMed: 10151049


Published online: 29 April 2009
Published in print: April 1994


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