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Published Online: 29 January 2014

The Clinical Research Office of the Endourological Society Ureteroscopy Global Study: Indications, Complications, and Outcomes in 11,885 Patients

Publication: Journal of Endourology
Volume 28, Issue Number 2


Purpose: To assess the current indications for ureteroscopy (URS) treatment, outcome in terms of stone-free rate, and intra- and postoperative complications using the modified Clavien grading system.
Patients and Methods: The Clinical Research Office of the Endourological Society collected prospective data as part of the URS Global Study for consecutive patients treated with URS at centers around the world for 1 year. URS was performed according to study protocol and local clinical practice guidelines. The stone size and location were recorded and postoperative outcome and complications, graded according to the modified Clavien grading system, reported.
Results: Between January 2010 and October 2012, 11,885 patients received URS at 114 centers in 32 countries; 1852 had only renal stones, 8676 had only ureteral stones, and 1145 patients had both types of stone. Fragmentation was performed principally using a laser device (49.0%) or a pneumatic device (30.3%); no device was used in 17.9% of the patients. A high stone-free rate (85.6%) was achieved. The large majority of patients did not receive any further treatment for renal or ureter stones (89.4%). The postoperative complication rate was low (3.5%). The most frequent complication was fever (1.8%); a blood transfusion was required in 0.2% of patients. The majority of complications were Clavien grade I or II (2.8% of patients).
Conclusion: URS is an established minimal invasive treatment for urinary stones with a high success rate and low morbidity. Recent advances have expanded the indication for urinary stones, which now ranges from treatment of smaller sized distal ureter stones by semirigid URS to larger sized renal pelvis stones treated by flexible URS.

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Published In

cover image Journal of Endourology
Journal of Endourology
Volume 28Issue Number 2February 2014
Pages: 131 - 139
PubMed: 24147820


Published in print: February 2014
Published online: 29 January 2014
Published ahead of print: 17 December 2013
Published ahead of production: 22 October 2013


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Jean de la Rosette
Department of Urology, AMC University Hospital, Amsterdam, The Netherlands.
John Denstedt
Department of Surgery, Western University, London, Ontario, Canada.
Petrisor Geavlete
Department of Urology, Saint John Emergency Clinical Hospital, Bucharest, Romania.
Francis Keeley
Bristol Urological Institute, Southmead Hospital, Bristol, United Kingdom.
Tadashi Matsuda
Department of Urology, Kansai Medical University, Osaka, Japan.
Margaret Pearle
Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas.
Glenn Preminger
Department of Urology, Duke University Medical Center, Durham, North Carolina.
Olivier Traxer
Department of Urology, Paris VI Pierre et Marie Curie, Paris, France.
on behalf of the CROES URS Study Group


Address correspondence to:Jean de la Rosette, MDDepartment of UrologyAMC University HospitalMeibergdreef 91105 AZ Amsterdam Z-OThe Netherlands
E-mail: [email protected]

Disclosure Statement

No competing financial interests exist.

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