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Published Online: 27 September 2006

Improvement in Human Semen Quality After Oral Supplementation of Vitamin C

Publication: Journal of Medicinal Food
Volume 9, Issue Number 3


This study was carried out to monitor the effect of oral supplementation of vitamin C on various semen parameters in oligospermic, infertile, otherwise healthy individuals. Various semen parameters, including sperm motility, sperm count, and sperm morphology, were studied before and after the vitamin C treatment. A total of 13 infertile patients were included. Their ages ranged between 25 and 35 years. They had no genital infection or varicocel. Physical examination and other routine laboratory investigations were normal. General semen analysis revealed oligozoospermia (mean sperm count was 14.3 ± 7.38 × 106 sperms/mL, mean sperm with normal morphology was 43 ± 7.87%, and mean sperm motility was 31.2 ± 9.61%). Testicular biopsy was not done. These patients received in an open trial of 1,000 mg of vitamin C twice daily for a maximum of 2 months. Results showed that the mean sperm count was increased to 32.8 ± 10.3 × 106 sperms/mL (P < .001) after 2 months of vitamin C intake. The mean sperm motility was increased significantly to 60.1 ± 8.47% (P < .001), and mean sperms with normal morphology increased significantly to 66.7 ± 4.77% (P < .001). This study showed that vitamin C supplementation in infertile men might improve sperm count, sperm motility, and sperm morphology and might have a place as an additional supplement to improve the semen quality towards conception.

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Published In

cover image Journal of Medicinal Food
Journal of Medicinal Food
Volume 9Issue Number 3Fall 2006
Pages: 440 - 442
PubMed: 17004914


Published online: 27 September 2006
Published in print: Fall 2006


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Mohammed Akmal
Dubai Specialized Medical Center & Research Labs, Dubai
J.Q. Qadri
Dubai Specialized Medical Center & Research Labs, Dubai
Noori S. Al-Waili
Al-Waili's Foundation for Science and Trading, Queens, New York
Shahiya Thangal
Dubai Specialized Medical Center & Research Labs, Dubai
Afrozul Haq
Medical Research & Specialized Testing Centre, Mafraq Hospital, Abu Dhabi, United Arab Emirates
Khelod Y. Saloom
Al-Waili's Foundation for Science and Trading, Queens, New York

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