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Published Online: 12 April 2011

The Emergence of Staphylococcus aureus ST398

Publication: Vector-Borne and Zoonotic Diseases
Volume 11, Issue Number 4

Abstract

The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) has changed dramatically over the past 15 years. Initially a nosocomial pathogen, newly emergent strains of MRSA have become increasingly common in the community among individuals lacking contact with healthcare. More recently, a third group of MRSA strains have been identified in association with livestock, particularly swine. These strains, termed livestock-associated MRSA, have now been identified in Europe, North America, and Asia in humans and animals. One molecular type, ST398, has been the dominant strain of livestock-associated MRSA identified to date. The emergence of this strain in animals and humans will be described in this review, including colonization and clinical infections caused by this strain. We also discuss lingering research questions and implications for controlling spread of this bacterium in an agricultural environment and beyond.

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cover image Vector-Borne and Zoonotic Diseases
Vector-Borne and Zoonotic Diseases
Volume 11Issue Number 4April 2011
Pages: 327 - 339
PubMed: 20925523

History

Published online: 12 April 2011
Published in print: April 2011
Published ahead of print: 6 October 2010

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Tara C. Smith
Department of Epidemiology, Center for Emerging Infectious Diseases, University of Iowa, Iowa City, Iowa.
Nicole Pearson
Department of Epidemiology, Center for Emerging Infectious Diseases, University of Iowa, Iowa City, Iowa.

Notes

Address correspondence to:Tara C. SmithDepartment of EpidemiologyCenter for Emerging Infectious DiseasesUniversity of IowaIowa City, IA 52242E-mail: [email protected]

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No competing financial interests exist.

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