Evaluation of Crimean-Congo Hemorrhagic Fever Virus Infection in Children
Publication: Vector-Borne and Zoonotic Diseases
Volume 13, Issue Number 11
Abstract
Crimean-Congo haemorrhagic fever (CCHF) is a fatal viral infection and an important public health issue in Turkey because of its high case fatality rate. Severity criteria of CCHF were defined previously in adults on the basis of epidemiological, clinical, and laboratory findings,. This study evaluated the course of CCHF in children. Between January, 2009, and November, 2012, 41 patients aged between 1 and 17 years (mean 9.78±4.85) with a diagnosis of CCHF were included in the study. According to results of our study, Turkish pediatric patients had a milder course of CCHF.
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References
Bakır MUgurlu MDokuzoguz BBodur H et al. Crimean-Congo haemorrhagic fever outbreak in Middle Anatolia: A multicentre study of clinical features and outcome measuresJ Med Microbiol200554385-389. Bakır M, Ugurlu M, Dokuzoguz B, Bodur H, et al. Crimean-Congo haemorrhagic fever outbreak in Middle Anatolia: A multicentre study of clinical features and outcome measures. J Med Microbiol 2005; 54:385–389.
Bishop DHBiology and molecular biology of bunyavirusesElliott RMThe BunyaviridaePlenum Press199619-61. Bishop DH. Biology and molecular biology of bunyaviruses. In: Elliott RM, ed. The Bunyaviridae. Plenum Press, 1996:19–61.
Burt FJLeman PASmith JFSwanepoel R et al. The use of a reverse transcriptionpolymerase chain reaction for the detection of viral nucleic acid in the diagnosis of Crimean-Congo hemorrhagic feverJ Virol Methods19987029-137. Burt FJ, Leman PA, Smith JF, Swanepoel R, et al. The use of a reverse transcriptionpolymerase chain reaction for the detection of viral nucleic acid in the diagnosis of Crimean-Congo hemorrhagic fever. J Virol Methods 1998; 70:29–137.
Centers for Disease Control and Prevention. Viral hemorrhagic fever: Initial management of suspected and confirmed casesMMWR Morb Mortal Wkly Rep19833227-38. Centers for Disease Control and Prevention. Viral hemorrhagic fever: Initial management of suspected and confirmed cases. MMWR Morb Mortal Wkly Rep 1983; 32:27–38.
Cevik MAErbay ABodur HGulderen E et al. Clinical and laboratory features of Crimean-Congo hemorrhagic fever: Predictors of fatalityInt J Infect Dis200812374-379. Cevik MA, Erbay A, Bodur H, Gulderen E, et al. Clinical and laboratory features of Crimean-Congo hemorrhagic fever: Predictors of fatality. Int J Infect Dis 2008; 12:374–379.
Charrel RNAttoui HButenko AM et al. Tick-borne virus diseases of human interest in EuropeClin Microbiol Infect2004101040-1055. Charrel RN, Attoui H, Butenko AM, et al. Tick-borne virus diseases of human interest in Europe. Clin Microbiol Infect 2004; 10:1040–1055.
Dilber ECakir MAcar EAOrhan F et al. Crimean-Congo haemorrhagic fever among children in north-eastern TurkeyAnn Trop Paediatr20092923-28. Dilber E, Cakir M, Acar EA, Orhan F, et al. Crimean-Congo haemorrhagic fever among children in north-eastern Turkey. Ann Trop Paediatr 2009; 29:23–28.
Ergonul OCelikbas ADokuzoguz BEren S et al. The characteristics of Crimean-Congo Hemorrhagic Fever in a recent outbreak in Turkey and the impact of oral ribavirin therapyClin Infect Dis200439285-289. Ergonul O, Celikbas A, Dokuzoguz B, Eren S, et al. The characteristics of Crimean-Congo Hemorrhagic Fever in a recent outbreak in Turkey and the impact of oral ribavirin therapy. Clin Infect Dis 2004; 39:285–289.
Ergonul OCelikbas ABaykam NEren S et al. Analysis of risk-factors among patients with Crimean-Congo haemorrhagic fever virus infection: Severity criteria revisitedClin Microbiol Infect2006a12551-554. Ergonul O, Celikbas A, Baykam N, Eren S, et al. Analysis of risk-factors among patients with Crimean-Congo haemorrhagic fever virus infection: Severity criteria revisited. Clin Microbiol Infect 2006a; 12:551–554.
Ergonul OTuncbilek SBaykam NCelikbas A et al. Evaluation of serum levels of interleukin (IL)-6, IL-10, and tumor necrosis factor-alpha in patients with Crimean-Congo hemorrhagic feverJ Infect Dis2006b193941-944. Ergonul O, Tuncbilek S, Baykam N, Celikbas A, et al. Evaluation of serum levels of interleukin (IL)-6, IL-10, and tumor necrosis factor-alpha in patients with Crimean-Congo hemorrhagic fever. J Infect Dis 2006b; 193:941–944.
Lilic DCant AJAbinun MCalvert JE et al. Cytokine production differs in children and adultsPediatr Res199742237-240. Lilic D, Cant AJ, Abinun M, Calvert JE, et al. Cytokine production differs in children and adults. Pediatr Res 1997; 42:237–240.
Ministry of Health2007Reports of the Communicable Diseases DepartmentMinistry of HealthAnkara, Turkey. Ministry of Health, 2007. Reports of the Communicable Diseases Department. Ministry of Health, Ankara, Turkey.
Ozkurt ZKiki IErol S et al. Crimean-Congo hemorrhagic fever in eastern Turkey: Clinical features, risk factors and efficacy of ribavirin therapyJ Infect200652207-215. Ozkurt Z, Kiki I, Erol S, et al. Crimean-Congo hemorrhagic fever in eastern Turkey: Clinical features, risk factors and efficacy of ribavirin therapy. J Infect 2006; 52:207–215.
Ozturk BTutuncu EKuscu FGurbuz Y et al. Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestionsInt J Infect Dis20121689-93. Ozturk B, Tutuncu E, Kuscu F, Gurbuz Y, et al. Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions. Int J Infect Dis 2012; 16:89–93.
Swanepoel RGill DEShepherd AJLeman PA et al. The clinical pathology of Crimean-Congo hemorrhagic feverRev Infect Dis198911794-800. Swanepoel R, Gill DE, Shepherd AJ, Leman PA, et al. The clinical pathology of Crimean-Congo hemorrhagic fever. Rev Infect Dis 1989; 11:794–800.
Tasdelen Fisgin NTanyel EDoganci LTulek N. Risk factors for fatality in patients with Crimean-Congo haemorrhagic feverTrop Doct200939158-160. Tasdelen Fisgin N, Tanyel E, Doganci L, Tulek N. Risk factors for fatality in patients with Crimean-Congo haemorrhagic fever. Trop Doct 2009; 39:158–160.
Tezer HSucakli IASayli TRCelikel E et al. Crimean-Congo hemorrhagic fever in childrenJ Clin Virol201048184-186. Tezer H, Sucakli IA, Sayli TR, Celikel E, et al. Crimean-Congo hemorrhagic fever in children. J Clin Virol 2010; 48:184–186.
Tuygun NTanir GCaglayik DYUyar Y et al. Pediatric cases of Crimean-Congo hemorrhagic fever in TurkeyPediatr Int201254402-406. Tuygun N, Tanir G, Caglayik DY, Uyar Y, et al. Pediatric cases of Crimean-Congo hemorrhagic fever in Turkey. Pediatr Int 2012; 54:402–406.
Vatansever ZUzun REstrada-Pena AErgonul O. Crimean-Congo hemorrhagic fever in TurkeyErgonul OWhitehouse CACrimean Congo Hemorrhagic Fever: A Global PerspectiveDordrecht, The NetherlandsSpringer200759-74. Vatansever Z, Uzun R, Estrada-Pena A, Ergonul O. Crimean-Congo hemorrhagic fever in Turkey. In: Ergonul O, Whitehouse CA (eds). Crimean Congo Hemorrhagic Fever: A Global Perspective. Dordrecht, The Netherlands: Springer, 2007:59–74.
Information & Authors
Information
Published In
Vector-Borne and Zoonotic Diseases
Volume 13 • Issue Number 11 • November 2013
Pages: 804 - 806
PubMed: 24107215
Copyright
Copyright 2013, Mary Ann Liebert, Inc.
History
Published online: 8 November 2013
Published in print: November 2013
Published ahead of print: 9 October 2013
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No competing financial interests exist.
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