Research Article
No access
Published Online: 17 October 2014

The Seroprevalence and Factors Associated with Ross River Virus Infection in Western Grey Kangaroos (Macropus fuliginosus) in Western Australia

Publication: Vector-Borne and Zoonotic Diseases
Volume 14, Issue Number 10

Abstract

A serosurvey was undertaken in 15 locations in the midwest to southwest of Western Australia (WA) to investigate the seroprevalence of Ross River virus (RRV) neutralizing antibodies and factors associated with infection in western grey kangaroos (Macropus fuliginosus). The estimated seroprevalence in 2632 kangaroo samples, using a serum neutralization test, was 43.9% (95% CI 42.0, 45.8). Location was significantly associated with seroprevalence (p<0.001). There was a strong positive correlation between seroprevalence and the average log-transformed neutralizing antibody titer (r=0.98, p<0.001). The seroprevalence among adult kangaroos was significantly higher than in subadult kangaroos (p<0.05). No significant association was observed between seroprevalence and the sex of kangaroos (p>0.05). The results of this study indicate that kangaroos in WA are regularly infected with RRV and may be involved in the maintenance and transmission of RRV.

Get full access to this article

View all available purchase options and get full access to this article.

References

Boyd A, Hall R, Gemmell R, Kay B. Experimental infection of Australian brushtail possums, Trichosurus vulpecula (Phalangeridae: Marsupialia), with Ross River and Barmah Forest viruses by use of a natural mosquito vector system. Am J of Trop Med Hyg 2001; 65:777–782.
Chalmers GA, Barrett MW. Capture Myopathy. Iowa: Iowa State University Press, 1982:88–94.
Dawson TJ. Kangaroos: Biology of the Largest Marsupials. Sydney: Comstock Publishing Associates, 2002.
Doherty RL, Standfast HA, Domrow R, Wetters EJ, et al. Studies of the epidemiology of arthropod-borne virus infections at Mitchell River Mission, Cape York Peninsula, North Queensland. IV. Arbovirus infections of mosquitoes and mammals, 1967–1969. Trans Roy Soc Trop Med Hyg 1971; 65:504–513.
Harley D, Sleigh A, Ritchie S. Ross River virus transmission, infection, and disease: A cross-disciplinary review. Clin Microbiol Rev 2001; 14:909–932.
Hill NJ, Power ML, Deane EM. Absence of Ross River virus amongst common brushtail possums (Trichosurus vulpecula) from metropolitan Sydney, Australia. Eur J Wildlife Res 2008; 55:313–316.
Johansen CA, Broom AK, Lindsay MDA, Maley FM, et al. Surveillance of arboviruses in mosquitoes from the southwest of Western Australia between 2000 and 2004. Arbo Res Aust 2005a; 9:159–163.
Johansen CA, Mackenzie JS, Smith DA, Lindsay MD. Prevalence of neutralising antibodies to Barmah Forest, Sinbis and Trubanaman viruses in animals and humans in the south-west of Western Australia. Aust J Zool 2005b; 53:51–58.
Johansen CA, Power SL, Broom AK. Determination of mosquito (Diptera: Culicidae) bloodmeal sources in Western Australia: Implications for arbovirus transmission. J Med Entomol 2009; 46:1167–1175.
Kay BH, Aaskov JG. Ross River virus (epidemic polyarthritis). In: Monath TP, ed. The Arboviruses: Ecology and Epidemiology. Boca Raton, Florida: CRC Press, 1989:93–112.
Kay BH, Hall RA, Fanning ID, Mottram P, et al. Experimental infection of vertebrates with Murray Valley encephalitis and Ross River viruses. Arbo Res Aust 1986; 4:71–75.
Kay BH, Pollitt CC, Fanning ID, Hall RA. The experimental infection of horses with Murray Valley encephalitis and Ross River viruses. Aust Vet J 1987; 64:52–55.
Kerr A, Whalley JM, Poole WE. Herpes virus neutralizing antibody in Grey kangaroos. Aust Vet J 1981; 57:347–348.
Kuno G. Persistence of arboviruses and antiviral antibodies in vertebrate hosts: its occurrence and impacts. Rev Med Virol 2001; 11:165–190.
Lindsay M, Oliveira N, Jasinska E, Johansen C, et al. Western Australia's largest recorded outbreak of Ross River virus disease. Arbo Res Aust 1997; 7:147–152.
Lindsay MD, Latchford JA, Wright AE, Mackenzie JS. Studies on the ecology of Ross River virus in the south west of Western Australia. Arbo Res Aust 1989; 5:28–32.
Lindsay MD, Condon R, Johansen C, D'Ercole M, et al. A major outbreak of Ross River virus infection in the south-west of Western Australia and the Perth Metropolitan area. Commun Dis Intell 1992; 16:290–294.
Marshall ID, Miles JAR. Ross River virus and epidemic polyarthritis. In: Harris KF, ed. Current Topics in Vector Research. New York: Praeger, 1984:31–56.
McCullagh P, Nelder J. Generalized Linear Models. London, England: Chapman and Hall, 1989:511.
Ng V, Dear K, Harley D, McMichael A. Analysis and prediction of Ross River Virus transmission in New South Wales, Australia. Vector Borne Zoonotic Dis 2014; 14:422–438.
Old JM, Deane EM. Antibodies to the Ross River virus in captive marsupials in urban areas of eastern New South Wales, Australia. J Wildlife Dis 2005; 41:611–614.
Pascoe RRR, George TDS, Cybinski DH. The isolation of a Ross River virus from a horse. Aust Vet J 1978; 54:600.
Russell RC. Ross River virus: Ecology and distribution. Annu Rev Entomol 2002; 47:1–31.
Whitehead RH, Doherty RL, Domrow R, Standfast HA, et al. Studies of the epidemiology of arthropod-borne virus infections at Mitchell River Mission, Cape York Peninsula, North Queensland. III. Virus studies of wild birds, 1964–1967. Trans R Soc Trop Med Hyg 1968; 62:439–445.

Information & Authors

Information

Published In

cover image Vector-Borne and Zoonotic Diseases
Vector-Borne and Zoonotic Diseases
Volume 14Issue Number 10October 2014
Pages: 740 - 745
PubMed: 25325318

History

Published online: 17 October 2014
Published in print: October 2014

Permissions

Request permissions for this article.

Topics

    Authors

    Affiliations

    Abbey Potter
    School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia, Australia.
    Cheryl A. Johansen
    School of Pathology and Laboratory Medicine, The University of Western Australia, Australia.
    Stan Fenwick
    School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia, Australia.
    Simon A. Reid
    School of Population Health, The University of Queensland, Queensland, Australia.
    Michael D.A. Lindsay
    Environmental Health Hazards, Department of Health, Western Australia, Australia.

    Notes

    Address correspondence to:Abbey PotterMosquito-Borne Disease ControlDepartment of HealthPO Box 8172Perth Business Centre, 6849Murdoch, WAAustralia
    E-mail: [email protected]

    Author Disclosure Statement

    No competing financial interests exist.

    Metrics & Citations

    Metrics

    Citations

    Export citation

    Select the format you want to export the citations of this publication.

    View Options

    Get Access

    Access content

    To read the fulltext, please use one of the options below to sign in or purchase access.

    Society Access

    If you are a member of a society that has access to this content please log in via your society website and then return to this publication.

    Restore your content access

    Enter your email address to restore your content access:

    Note: This functionality works only for purchases done as a guest. If you already have an account, log in to access the content to which you are entitled.

    View options

    PDF/EPUB

    View PDF/ePub

    Full Text

    View Full Text

    Media

    Figures

    Other

    Tables

    Share

    Share

    Copy the content Link

    Share on social media

    Back to Top